Research
1
Adhesive hydrogel for photoactivated tissue regeneration and drug delivery
We are fabricating adhesive, therapeutic hydrogels in the form of membranes or patches. These adhesive hydrogels can be used for photoactivated drug delivery and tissue sealing during surgeries. We are also integrating bioluminescent agents into the hydrogels to enable phototherapy for tissue regeneration and antimicrobial effects. The mechanical properties of the hydrogels will be tailored based on their specific biological applications.
2
Biolaser probe for in vivo
tracking, diagnosis, and photobiomodulation
We design various lasing materials with biopolymers. These materials serve as probes within diverse in vivo systems to uncover biological phenomena. They are engineered to possess deep-tissue tracking capabilities. These probes are capable of detecting/sensing environmental changes in cells/tissues and will be utilized for diagnostic purposes.
3
Optical coherence elastography for soft tissue diagnosis and materials characterization
This novel optical device enables in situ, noninvasive mechanical characterization of soft tissues and biomaterials. It is designed to replace conventional invasive characterization methods. Additionally, it can be applied to detect internal defects and spatial heterogeneity within tissue/biomaterials to diagnose diseases.
4
Clinical evaluation of
dental biomaterials
Dental biomaterials must possess appropriate mechanical, chemical, optical, and biological properties for use in clinical settings. Evaluating and optimizing these properties is essential translational research for the improvement and development of advanced dental biomaterials.
